Abstract
I have no intention of trying to summarise or comment on the wide range of areas covered under the very general title of this meeting. Partly because, to use a colloquial English expression, I am knackered by a combination of scientific concentration and social excess. Partly because the science has been presented in such a way that for me to reinterpret and comment on it would be redundant. On the other hand, I have often been accused of never being able to keep my mouth shut and given this captive audience, it hardly seems the place to alter the habits of a lifetime. So before travel plans and exhaustion intervene too much, I will take the opportunity to make some very brief general comments.